Role of Trans-Vaginal Ultrasonography for Comparative Analysis of Ovarian Volume and Antral Follicle Count for Predicting the Retrieved Oocyte Number, In IVF Patients

Aims and Objectives a To compare the role of pre-induction ovarian volume and antral follicle count in predicting the retrieved oocyte numbers in in-vitro fertilization patients (IVF). b To study the co-relation of ovarian volume with antral follicle count. Methods and Materials: 53 infertile patients were randomly taken in the study. On 2 day of cycle, Transvaginalultrasound was done and pre-induction total ovarian volume (TOV) and total antral follicle count (TAFC) were calculated. Ovarian volume was calculated using ellipsoid formula and total volume was considered by adding volume of both the ovaries. Ovulation was induced using clomiphene citrate from day 3 to 7 of cycle. Post induction oocyte retrieval was done on mid cycle by the IVF team and total oocyte count (TOC) was considered. Results: Mean age was 30.11±3.6, Mean TAFC was 11.98±5.69, mean TOV was 8.27±2.19cm and mean TOC was 9.38 ±4.5. Correlation coefficient for TAFC and TOC was 0.959 with p value of <0.0001. Correlation coefficient for TOV and TOC was 0.726 with p value of <0.0001. Correlation coefficient for TAFC and TOV was 0.796 with p value of <0.0001. Conclusion: TAFC and TOV both are significant predictors of retrieved TOC. TAFC is a better predictor with high coefficient of determination of 94.5% and a low standard error of 0.55 as compared to TOV. Also TAFC and TOV are significantly correlated. As AFC increases TOV also increases.